BTK blockers make headway in multiple sclerosis

Elie Dolgin • January 11, 2021

By targeting both arms of the immune system, not just B cells, brain-penetrant inhibitors of Bruton’s tyrosine kinase could improve on anti-CD20 therapy for patients with multiple sclerosis.

Continue reading at Nature Biotechnology.

‘Connectoids’ use microfluid channels to recapitulate and study neural connections.
By Elie Dolgin May 14, 2025
With organoids, assembloids and a growing bioengineering toolkit, scientists are pushing the limits of human brain models.
Picture of scientist handling mRNA, Robert F. Kennedy Jr. and vaccine protesters.
By Elie Dolgin May 9, 2025
Drug makers are scrambling to navigate an ‘existential threat’ to a once-celebrated technology.