Hope for diabetes: CRISPR-edited cells evade immune detection
Elie Dolgin • September 5, 2025
Edits create cells that don’t trigger an immune response, allowing implant recipient to forego immune-suppressing drugs.
In a medical first, researchers report that they have implanted CRISPR-edited pancreas cells into a person with type 1 diabetes. The cells pumped out sugar-regulating insulin for months — without the need for the recipient to take immune-dampening drugs, thanks to gene edits that allowed the cells, collected from a deceased donor, to evade detection by the recipient’s immune system.
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