Laser-boosted microscopy opens view of elusive proteins
Elie Dolgin • June 11, 2026
Enhanced cryo–electron microscopy promises to bring previously elusive proteins into view.
By flash freezing proteins and bombarding them with electrons, cryo–electron microscopy (cryo-EM) has transformed structural biology, revealing the shape of thousands of proteins that were impossible to crystallize and decode through traditional x-ray analysis. Now, a laser-powered upgrade could extend the technique’s reach even further, bringing some of its smallest and most elusive targets into view.
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